In 1985, the murder of a government-sponsored superhero draws his outlawed colleagues out of retirement and into a mystery that threatens to upend their personal lives and the world itself.
Suspicious of the events ensnaring their former colleagues, Nite Owl and Silk Spectre are spurred out of retirement to investigate. As they grapple with personal ethics, inner demons and a society turned against them, they race the clock to uncover a deepening plot that might trigger global nuclear war.
Determined to prove he's the world's greatest supervillain, Gru hatches an audacious plan to steal the Moon. To pull it off, he adopts three orphaned girls—Margo, Edith, and Agnes—intending to use them as pawns in his scheme. But the unexpected bond they form forces him to question the criminal life he's always known.
Gru and Lucy and their girls—Margo, Edith and Agnes—welcome a new member to the Gru family, Gru Jr., who is intent on tormenting his dad. Gru also faces a new nemesis in Maxime Le Mal and his femme fatale girlfriend Valentina, forcing the family to go on the run.
A fanboy of a supervillain supergroup known as the Vicious 6, Gru hatches a plan to become evil enough to join them, with the backup of his followers, the Minions.